Prognostic significance of flow cytometric DNA analysis in node-negative breast cancer patients
نویسندگان
چکیده
منابع مشابه
Prognostic value of flow-cytometric DNA analysis in breast cancer
The most important factor influencing prognosis in breast cancer is its biological aggressiveness, generally expressed by parameters such as tumor size, number of metastatized lymph nodes, histological grade and receptors status. In recent years, the proliferative rate of tumors has been widely investigated in an attempt to define additional prognostic factors. New factors have thus been propos...
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PURPOSE RON and MET belong to a subfamily of tyrosine kinase receptors. They both can induce invasive growth, including migration, cell dissociation, and matrix invasion. Cross-linking experiments show that RON and MET form a noncovalent complex on the cell surface and cooperate in intracellular signaling. We wanted to examine the clinical significance of RON and MET expression patterns in node...
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In gynecologic oncology valid prognostic factors are necessary to estimate the course of disease and to define biologically similar subgroups for analysis of therapeutic efficacy. The presented study is a prospective study concerning prognostic significance of DNA ploidy and S-phase fraction in breast cancer following enrichment of tumor cells by cytokeratin labelling. Epithelial cells were lab...
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More accurate prediction of the prognosis in women with node-negative breast cancer may improve physicians' ability to identify the patients most likely to benefit from systematic adjuvant therapy. With this in mind, we performed DNA flow-cytometric measurements of ploidy and the fraction of cells in the synthesis phase of the cell cycle (S-phase fraction) on 395 specimens of node-negative brea...
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ژورنال
عنوان ژورنال: Cancer
سال: 1990
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19900515)65:10<2315::aid-cncr2820651025>3.0.co;2-3